The School of Life Science and Technology of Shanghai Jiaotong University has developed the Pseudomonas fluorescens strain M18 with its own intellectual property rights. It has pioneered the development of a broad-spectrum, high-efficiency, safe biological pesticide that can effectively control fungal root rot and stem rot. , named "Shenzinmycin". Futation of cucumber and watermelon, blight of melon, root rot of pepper, and other stubborn diseases that are difficult to cure. M18 is an antibiotic isolated from a variety of autogenous bacteria in the rhizosphere soil of crops. It can broadly inhibit various crop pathogenic fungi, and has the advantages of high-efficiency control of diseases, promotion of high yield and quality of crops, and protection of ecological environment. After many years of research, Shanghai Jiaotong University's College of Life Science and Technology has carried out research on the prevention and treatment of melon wilt disease by the implementation of dual-function growth-promoting bacteria in the key projects of science and technology in agriculture in Shanghai, the cloning and functional study of bio-pesticide carboxyphenazine-encoding genes and bio-pesticides. The development of minocycline (M18) obtained M18. Researchers have conducted in-depth research on M18, and developed high-yield genetic engineering strains, and stabilized the Shenzinmycin fermentation unit at about 1000 mg/L, and the pilot fermentation level reached 800 mg/L or more. The research team has conducted experiments in various places, and the average control effect of chlorpyrifos on blight, wilt and root rot is 80%. With the support of the project, Shanghai Jiaotong University Life Science Academy has teamed up with Shanghai Nongle Biological Products Co., Ltd. to complete the development of 0.1% and 1% Shensinmycin suspension agent and established a pilot production line. It has promoted the use of 50 tons of preparations and realized sales income of 5 million yuan. At present, the college has applied for two invention patents of Shenzinmycin. At present, the annual incidence of fungal root rot and stem rot of fruits and vegetables in China exceeds 25 million mu times, and economic losses amount to several billion yuan. The annual incidence of the suburbs of Shanghai is about 40,000 mu, and the economic loss is nearly 150 million yuan. For a long time, the main means of controlling these diseases have been to spray chemical agents such as chlorpyrifos and thiophanate. The residues of pharmaceuticals not only affect food safety and quality, but also pollute the ecological environment.
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