Diagnosis and treatment of mixed infection of swine fever and streptococci

In recent years, due to the widespread prevalence of porcine circovirus type 2 (PCV2) and mycotoxin-induced immunosuppression in pig herds, mixed infections in pigs are becoming more common. It brings great challenges to clinical diagnosis and also causes great losses to the majority of farmers.
In this paper, a mixed infection was diagnosed by clinical dissection and laboratory testing:
In this case, the pig farm has been dead since the beginning of last year. The pigs have alternating diarrhea and constipation, and then they are dehydrated and die. Some of the big pigs can be resistant to becoming dead pigs. Both cephalosporins and enrofloxacin are ineffective.
First, through clinical dissection, the results are shown below:


Figure 1. Whole body subcutaneous bleeding point


Figure 2, heart fat bleeding


Figure 3. The kidney has a needle-like bleeding point.


Figure 4. Renal plaque-like hemorrhage


Figure 5. Bladder bleeding


Figure 6. Lymph node hemorrhage


Second, the results of the detection of 5 samples (all sows) on the farm are as follows:

　

Positive/head

Negative/head

Positive rate

Eligibility criteria

Pass rate

Swine fever

2

3

20%

100%

Failed

Blue ear

5

0

100%

S/P value 07-1.8

qualified

Pseudo rabies

5

0

100%

100%

qualified


Third, the bacterial isolation and drug susceptibility test are as follows:
Staining microscopy Gram-positive streptococci
Training characteristics Inoculated with yak serum containing fine droplets, glitter, grayish white, round and slightly convex, smooth surface, neatly arranged colonies
Biochemical test Glucose, maltose, sucrose, mannitol, lactose, vp, methyl red biochemical tubes are consistent with the reaction of streptococcus
Isolation and purification identification Streptococcus
drug allergy testing Shows that doxycycline is extremely sensitive, sensitive to florfenicol, gentamicin, kanamycin, lincomycin hydrochloride, amoxicillin

Fourth, case analysis

According to the epidemiology of pig farms, the typical clinical dissection lesions of swine fever and streptococci combined with laboratory antibody detection and bacterial isolation can diagnose the sows with long-term toxicity due to unqualified swine fever, and the pigs are immune to tolerance. Or plus the usual feed, vaccine management improperly affected by mycotoxins, vaccine quality, etc., the body's resistance is insufficient secondary to secondary infection of streptococcus.
V. Prevention and control measures 1. The pig house and the environment shall be disinfected with a ratio of 1:500, 1 time/day.
2. The whole group will replenish the piglets with better effect on the market (increase the dose), re-examine them after half a month, and eliminate the unqualified sows. A mildew remover such as mildew (3 kg/ton) is added to the batch.
3. Treatment:
1 For pigs with serious illness, each pig was intramuscularly injected with florfenicol + VB12+VC.
2 whole group drinking water: doxycycline hydrochloride (doxycycline) 200 grams to 300 grams / ton + amoxicillin soluble powder 0.25 kg / 500 kg water, for 3-5 days.
3 Mixture: In the whole group of ingredients, add lung Anchangkang (lincomycin, spectinomycin) 1 kg / ton + Vitokang 100 g / 100 kg + times Jiakang 1 kg / ton, for 7 days.

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